2024 Agenda
*All times are in CEST
Sep
Thu 19
Welcome reception
Sep
Fri 20
Introduction & Meeting Objectives
John Gribben
Session 1: T-cell Leukemia/Lymphoma
Chairs: Laurence de Leval & Francine Foss
Overview Lecture: LGL Leukemia – current treatments and perspectives: TBC
- T-PLL: Advances and Perspectives: TBC
- HTLV-1 ATLL: Contemporary Outcomes: Lucy Cook
- Current and future treatment approaches in T-cell lymphoma: Francine Foss
- AUTO4 (TRBC1 directed autologous CAR-T) in TRBC1-positive PTCL: Kate Cwynarski
Panel Discussion
Break
Session 2: Evolving frontline immune-chemotherapy for MCL and the impact on survival outcomes
Chairs: Stephen Ansell & Elaine Jaffe
- How do genetics and pathology of MCL guide treatment decisions? TBC
- Has frontline therapy for MCL changed from intensive chemo-based to targeted small molecule -based?: John Kuruvilla
- Should frontline treatment for MCL be ‘chemo-free’ – where do cellular therapies fit in?: TBC
- Has maintenance therapy replaced ASCT in MCL?: Michael Williams
- New strategies to manage relapsed MCL: Caron Jacobson
Panel Discussion: Remaining gaps and perspectives
Session 3: Keynote address
Chair & Introduction: Carmelo Carlo-Stella
Modelling the crosstalk between malignant B cells and their microenvironment in B-cell lymphomas: challenges and opportunities: TBC
Panel Discussion
Lunch
Session 4: Novel Therapies
Chairs: John Gribben & Laurie Sehn
- Novel drug development: an industry perspective: Simon Rule (Astra Zeneca)
Industry Panel Discussion
ADCs:
- Polatuzumab vedotin: Laurie Sehn
- Zilovertamab: Sven De Vos
- Loncastuximab Tesirine: Paolo Caimi
- Camidanlumab: Andrew Davies
- Emerging ADCs with novel targets: Juan Pablo Alderuccio
- DBCL: Alex Herrera
Panel Discussion
Break
Session 5: Debate
Chairs: Anna Sureda & Catherine Bollard
“Should CD19 CAR-T cell treatment be selected by age and co-morbidity?”
Jason Westin (NO)
TBC (YES)
Panel Discussion
Day 1 wrap-up
Sep
Sat 21
Session 6: Expanding the CAR platform for NHL
Chairs: David Maloney & TBC
- Tis-a-cel: TBC
- Axi-cel: Sattva Neelapu
- Liso-cel: David Maloney
- CD20 CAR-T (MB-106): TBC
- Rapcabtagene: TBC
- CB-010: TBC
Panel Discussion (15 min)
- Development of CAR-T platforms for T-cell lymphomas: Laquisa Hill
- CAR-T vs Auto HCT in first relapse – is auto-HCT dead?: Jason Westin
- Strategies to minimize toxicity of CAR-T cell treatment: Caron Jacobson
- Allogeneic CAR-T cells: Is there a strategy moving forward?: TBC
- CAR-T for CLL. Where do we stand? Who and when do we treat?: Tanya Siddiqi
Panel Discussion: CAR-T in the real-world setting
Break
Session 7: Special Topic
Introduction: Riccardo Dalla-Favera
The germinal center in the pathogenesis of B cell lymphomas: Laura Pasqualucci
Panel Discussion
Session 8: Novel Therapies part 2
Chairs: Laurie Sehn & TBC
- LYSA in a nutshell: TBC
BTK Inhibitors:
- Is there till a role for ibrutinib?: TBC
- Zanubrutinib: Pier Luigi Zinzani
- Acalabrutinib: Stephen Ansell
- Pirtobrutinib: TBC
Panel Discussion
BTK Degraders:
- NX-2127 & NX-5948: Alexey Danilov
- NX-5948: TBC
BCL-2 inhibitors:
- BGB-11417 (sonrotoclax): TBC
- Novel venetoclax combinations: Tanya Siddiqi
- ViPOR regimen in DLBCL: Jordan Goldstein
Panel Discussion
Lunch
Session 9: Bispecific antibodies for NHL
Chairs: Martin Hutchings & Marion Subklewe
CD3/CD20 bispecifics and their quest for ideal partners
- Glofitamab: Martin Hutchings
- Mosunetuzumab: TBC
- Odronextamab: Stephen Ansell
- Epcoritamab: Martin Hutchings
- Plamotamab: TBC
Panel Discussion
Break
Bispecific and trispecifics with other formats and targets
Chairs: TBC
- Imvotamab: TBC
- TNB 486: TBC
- Other bi- and tri-specific antibodies in early development: Marion Subklewe
Panel Discussion: Future directions
Final Meeting Summary & Conclusions: iwNHL Committee