Agenda

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This agenda is the latest draft and subject to change. We are working on further details and will update this page as soon as possible.

*All times are in CEST

Sep

Fri 26

6:30pm -8:00pm

Welcome reception

Sep

Sat 27

08:45am -09:00am

Introduction & Meeting Objectives
John Gribben

09:00am -10:30am

Session 1:  T-cell Leukemia/Lymphoma
Chairs: Laurence de Leval & Francine Foss

 

Special Lecture: T-cell Leukemia/Lymphoma

  • Pre-clinical models for precision therapy in TCLs; Francois Lemonnier
  • Epidemiology and predictive models of relapse refractory T-cell lymphoma; Salvia Jain
  • Pathology classification and recent advances, if we want to put a focus on CTCL; TBC
  • Aggressive T-cell lymphoma in refractory patients; Francine Foss
  • Epigenetic therapies in PTCLs; TBC
  • Evolving therapies in TCL (CAR-T, BsAbs, VALEMETOSTAT & VALENTINE); Pier Luigi Zinzani

 

Roundtable Discussion

10:30am -10:50am

Break

10:50am -12:00pm

Session 2: Session II:  MCL
Chairs: Stephen Ansell & TBC

 

  • Evolution of  Mantle Cell lymphoma(s):  From Conception to the Current Reality; Elaine Jaffa 
  • Frontline therapy for MCL – which patient needs which initial regimen?; TBC
  • Consolidation after frontline therapy – is autologous stem cell transplantation for MCL a thing of the past?; TBC
  • How to use MRD to manage MCL; TBC
  • Small molecule inhibitors for relapsed MCL – one at a time or all together? Tycel Phillips

 

Panel Discussion: Remaining gaps and perspectives

12:00pm -1:00pm

Session 3: Keynote address
Chair & Introduction: John Gribben

Keynote: Capturing and targeting the molecular heterogeneity in diffuse large B-cell lymphoma; Margaret Shipp

 

Panel Discussion

1:00pm -2:00pm

Lunch

2:00pm -4:10pm

Session 4: Novel therapies I
Chairs: Jason Westin & TBC

 

Industry Panel Discussion: Simon Rule

  • Harmonized criteria for reporting of imaging in CRFs; an industry perspective; TBC
  • ODAC regulatory perspectives on CRFs in Lymphoma; TBC

 

Roundtable discussion

 

 

McAbs and ADC Combinations:

  • Brentuximab combinations; Loretta Nstoupil
  • Tafasitamab combinations, Laurie Sehn
  • Zilovertamab combinations; TBC
  • Loncastuximab combinations; Juan Pablo Alderuccio
  • Polatuzumab combinations; Gilles Salles
  • What’s next in Mab’s and ADC’s?; TBC
  • Finding the right combination- The value and limits of preclinical studies; TBC

 

Roundtable Discussion

4:10pm -4:30pm

Break

4:30pm -6:00pm

Session 5: Special Topic: Hodgkin’s Lymphoma
Chairs: Rnjana Advani & TBC

 

  • Early stage HL; Stephen Ansell
  • Adv stage HL; Ranjana Advani
  • 2nd Line treatment; TBC
  • Beyond 2nd line; Alex Herrera
  • Elderly HL; Sarah Rutherford
  • 1st Line AYA; TBC

 

Panel Discussion

6:00pm -6:10pm

Day 1 Wrap Up

Sep

Sun 28

8:30AM -10:40AM

Session 6: Bispecific antibodies in 1st and 2nd line treatment of FL and DLBLC   
Chairs: Martin Hutchings & TBC

 

CD3/CD20 bispecifics in early lines of treatment in FL and LBCL

  • Mosunetuzumab; TBC
  • Epcoritamab combinations; Lorenzo Falchi
  • Glofitamab combinations; Martin Hutchings
  • Plamotamab; combinations; Tycel Phillips
  • Odronextamab; TBC
  • AZD0486; Sameh Gaballa

 

Roundtable Discussion

 

Bispecific and trispecifics with other formats and targets

  • Imvotamab; TBC
  • Future perspectives with bi-and trispecific antibodies; Jason Westin

 

Roundtable Discussion: Future Directions 

10:40am -11:10am

Break

11:10am -1:00pm

Session 7: Novel Therapies
Chairs: Laurie Sehn & Alexey Danilov

 

BTK Inhibitors combinations:

  • Ibrutinib; Loretta Nastoupil
  • Zanubrutinib combinations; Pier Luigi Zinzani
  • Acalabrutinib combinations; Krish Patel 
  • Pirtobrutinib combinations; Michael Wang

BTK Degaraders: 

  • BGB-16673; Megan Thompson
  • NX-2127 and NX5948; Alexey Danilov

BCL-2 inhibitors:

  • Sonrotoclax; Steve Treon
  • Whats’ new in targeted therapy? Sonali Smith

Roundtable Discussion

 

1:00pm -2:00pm

Lunch

2:00pm -3:50pm

Session 8: Expanding the CAR platform for NHL
Chairs: David Maloney & Cath Bollard

Real World Data:

  • Liso-cel for DLBCL; Jeremy Abramson
  •  Axi-cel; Sattva Neelapu
  •  Tis-a-cel; TBC
  •  Future perspectives – where do we go from here? Jason Westin

e-break (15 min)

  • Molecular Disease Monitoring in Patients With R/R B-Cell Lymphoma; TBC
  • Rapcabtagene; TBC
  • CD20 CAR-T; Mazyar Shadman
  • Multi-targeted CARs; TBC
  • Allogeneic CAR-T cells: Is there a strategy moving forward?; TBC
  • CB-010 (anti-CD19 CAR-T); TBC

 

Roundtable Discussion: CAR-T in the real-World Setting

 

3:50pm -4:00pm

Final Meeting Summary and Conclusions
Chairs: iwNHL Committee

 

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